Cannabidiol at a dose of 2-5 mg / kg / day divided into two doses was added to the basic antiepileptic regimen, and then was increased by 2-5 mg / kg once a week until intolerance or until a dose was reached maximum of 25 mg / kg / day. In some places, the institutional review board and the Food and Drug Administration of the United States (FDA) allowed the increase to a maximum dose of 50 mg / kg / day.
During the first three months of treatment with cannabidiol CBD Gummies, efforts were made to maintain concomitant doses of the antiepileptic drug constant. However, in some cases, sedation after the addition of cannabidiol led to decreases in such antiepileptic drugs, as clinically indicated. No concomitant antiepileptic drug was discontinued during the study.
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